What is Peyronie’s disease?

Peyronie’s disease is an unusual wound healing condition caused by fibrous scar tissue on the penis that causes curved and painful erections. In many cases, a hard lump can be felt at the point where the penis curves. The hardened area prevents the usual enlargement and affects the size and form of the erect penis.

There are usually two steps in Peyronie’s disease:
Active phase: It is the phase where there is pain during erection and represents the onset of the disease. May cause slight curvature of the penis. It usually takes 6-12 months.
Stable phase: pain decreases but curvature actually increases towards the end of the active phase and remains unchanged in this phase in its now chronic form.

How common is Peyronie’s disease?
The exact frequency is not known because many men do not notice the problem, are too embarrassed to see a doctor, or do not seek help because the symptoms are mild. Although it is seen at higher rates in patients with erectile dysfunction and diabetes, it is seen in the middle of 1-20% of the population.

What causes Peyronie’s disease?
The causes of Peyronie’s disease are unclear, but it is thought to occur after repetitive microvascular injury or trauma. Rupture of erectile tissue leads to an inflammatory plaque (scar tissue) that does not normally heal. Often this type of injury causes swelling and heals on its own. A pre-existing problem with the immune system or diabetes may explain why some men develop PH after an easy penile injury, while others survive the injury. PD mostly affects boys after puberty, but the most common age group is between the ages of 45 and 60.

How is Peyronie’s disease diagnosed?
A gynecologist can simply diagnose Peyronie’s based on the medical history and physical exam. But for the physician to understand how much the penis is bent, the penis must be erect. Patients who are afraid of getting an erection while in the hospital can take a photo of their erect penis at home and show it to their physician when they arrive. Observing the curvature while the penis is erect is essential for the treatment and determination of the type of operation required for surgery.

How is Peyronie’s disease treated?
Peyronie’s disease is often managed depending on the severity of the curve, the degree of inflammation present, difficulty with sexual interest, and how much it bothers the patient. Watchful waiting – If the curve is not severe and the pain is mild and easily relieved with painkillers, the patient can wait and watch if the curve worsens. Drug therapy – includes administration of anti-inflammatory, vitamin E, colchicine, potassium paraaminobenzoate depending on the availability of drugs. These drugs may or may not reduce the curvature, but provide relief from inflammation in the plaque. Intraplaque injection- verapamil-PRP-Collagenase of Clostridium histolyticum is used with intermittent injections. Surgery- curvature correction (cavernous layer)/Nesbit surgery/LUE procedure/penile
implants, depending on the curvature of the penis and erectile function. Surgery is often the most preferred treatment option in patients with long-standing Peyronie’s disease and a stable curve. Shockwave therapy – this therapy is new, non-invasive, painless and useful for patients with mild curvature.

When Is Surgery Performed in Peyronie’s Disease?
If the curvature is not much and there is no roughness on the interest, we first apply the P-Shot treatment. P-Shot aggravates the adaptation and growth factors in the patient’s own blood into an injectable treatment. It is applied to the plaque tissue by your doctor. Complaints such as the continuation of pain during erection, the curvature that interferes with intercourse, the formation of erectile dysfunction and the development of fear disorder in the individual require surgical planning. The penis is corrected by making a plication process with stitches on the opposite side of the side of the penis with plaque formation. If the curvature is excessive, the plates are removed, and the vein and vein prepared from animals are placed in the cavity.
skin grafts, patches are transplanted. If there is an erection problem in the penis, a penile prosthesis is placed.

The treatment success rate is over 80%. As in every disease, we also apply personalized treatments at Peyronie’s. As a result of the examination and tests, you will be offered treatment options.